Thursday, July 19, 2012

Drinking Red Wine linked With Reduced Lung Cancer Risk in Male Smokers

Kaiser Permanente - Drinking Red Wine linked With Reduced Lung Cancer Risk in Male Smokers
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In the October, 2008 issue of the American relationship for Cancer research journal Cancer Epidemiology, Biomarkers & Prevention¸ California Kaiser Permanente researchers description yet an additional one benefit connected with drinking red wine: a lower risk of lung cancer.

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How is Drinking Red Wine linked With Reduced Lung Cancer Risk in Male Smokers

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Chun Chao, PhD, of Kaiser Permanente's agency of research and assessment in Pasadena, California, and colleagues analyzed data from the California Men's health Study of 84,170 men aged 45 to 69. Surveys completed between 2000 and 2003 in case,granted data with regard to demographics and lifestyle characteristics, along with type and frequency of alcoholic beverage consumption. Over the three year period, 210 cases of lung cancer were identified.

Among men who reported ever having smoked, drinking one or more glasses of red wine per day was connected with a 61 percent lower adjusted risk of lung cancer compared to the risk experienced by those who did not consume red wine. For each glass of red wine consumed per month, a 2 percent discount in lung cancer risk was noted among those who had ever smoked, and for those who reported having been heavy smokers, a 4 percent discount was observed. No follow for beer, liquor, or white wine was observed.

"An antioxidant component in red wine may be protective of lung cancer, particularly among smokers," Dr Chao stated. "Red wine is known to comprise high levels of antioxidants. There is a mixture called resveratrol that is very rich in red wine because it is derived from the grape skin. This mixture has shown indispensable health benefits in preclinical studies."

Although white wine also contains beneficial phytochemicals, their level and activity are much lower compared with those found in red wine. The authors discover that resveratrol, found in red wine, red grapes, and other plants, has been shown to alter the activation of carcinogenic substances in human lung cell cultures, induce programmed cell death in human lung cancer cell lines, and slow lung tumor increase in experiments with mice.

"This finding, if confirmed is of interest for lung cancer chemoprevention in current and former smokers," the authors write. They emphasize that not smoking is still the best way to avoid lung cancer, and that heavy alcohol consumption is not recommended.

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